Dietary Treatment Study of Fat Synthesis and Risk of Cardiovascular Disease

Summary

The purpose of this study is to find out how the amount of fat or sugar in a person's diet, or the number of meals eaten each day, affect the amount of fat that people's bodies make, the types of fats in the bloodstream, and how much fat is stored in the liver. The study is funded by the National Institutes of Health.

Conditions

• Overweight and Obesity

Interventions

OTHER

High sugar/meal feed

Weight-maintaining diet relatively high in sugar fed as two large meals daily

OTHER

High sugar/nibble

Weight-maintaining diet relatively high in sugar fed as 8 meals daily

OTHER

High fat/meal feed

Weight-maintaining diet relatively high in fat fed as two large meals daily

OTHER

High fat/nibble

Weight-maintaining diet relatively high in fat fed as 8 small meals daily

OTHER

High sugar/ 3 meals a day

Weight-maintaining diet relatively high in sugar fed as 3 meals daily

OTHER

High fat/ 3 meals a day

Weight-maintaining diet relatively high in fat fed as 3 meals daily

Sponsors & Collaborators

• Touro University, California

  collaborator OTHER

• University of California, San Francisco

  lead OTHER

Principal Investigators

• Kathleen Mulligan, PhD · University of California, San Francisco

• Jean-Marc Schwarz, PhD · Touro University, California

Study Design

Allocation

RANDOMIZED

Purpose

OTHER

Masking

DOUBLE

Model

FACTORIAL

Eligibility

Min Age

20 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2013-07-31

Primary Completion

2022-12-31

Completion

2022-12-31

Countries

• United States

Study Locations