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The Salty Gut: Effects of High Dietary Salt Intake on the Gut Microbiota

NCT04229680 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 31

Last updated 2023-10-02

No results posted yet for this study

Summary

Gut microbiota has a role in cardiovascular disease and recent findings in rodents show dietary salt can negatively alter gut microbiota composition. High salt intake is a risk factor for cardiovascular disease. Americans consume dietary salt in excess of Dietary Guidelines and American Heart Association recommendations. The objective of this project is to investigate the influence of high dietary salt consumption on the gut microbiota composition in men and women.

Conditions

  • Cardiovascular Risk Factor

Interventions

OTHER

High Salt

Consumption of pills containing table salt for 10 days.

OTHER

Recommended Salt

Consumption of pills containing dextrose for 10 days.

Sponsors & Collaborators

  • University of Delaware

    lead OTHER

Principal Investigators

  • Shannon L Lennon, PhD, RD · University of Delaware

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-04-16
Primary Completion
2021-02-24
Completion
2021-02-24

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04229680 on ClinicalTrials.gov