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Health Effects of Sustainable Future Proteins

NCT03744221 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2019-01-16

No results posted yet for this study

Summary

In the current study the investigators aim to assess the nutritional quality and bio-functional activity of two alternative protein sources bovine plasma and corn and from the benchmark protein whey. The study is a double blind, randomised, cross-over, short-term trial in which 36 healthy study subjects will receive three protein interventions of 1 week with a washout period of 1 week between interventions. Study subjects will visit the research facility before and after the intervention period on two separate occasions to measure gut permeability via a multi-sugar test and to collect fasting blood samples and blood pressure outcomes. Faecal and saliva samples before and after each intervention will be collected. A subgroup of 12 study participants will also be subjected to a postprandial digestibility test on the first day of the interventions. The main study parameter is to assess the protein digestion kinetics and protection of the epithelial barrier. Secondary study parameters include other markers of gastrointestinal health, metabolic health, vascular health and satiating properties.

Conditions

  • Intestinal Barrier Function
  • Protein Digestion Kinetics

Interventions

DIETARY_SUPPLEMENT

Corn protein powder

40g/d ( 2 times 20 grams per day for a period of 1 week)

DIETARY_SUPPLEMENT

Bovine plasma protein powder

40g/d ( 2 times 20 grams per day for a period of 1 week)

DIETARY_SUPPLEMENT

Whey protein powder

40g/d ( 2 times 20 grams per day for a period of 1 week)

Sponsors & Collaborators

  • Wageningen University and Research

    lead OTHER

Principal Investigators

  • Diederik Esser, Dr · Wageningen research

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
35 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-11-05
Primary Completion
2018-12-20
Completion
2018-12-20

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03744221 on ClinicalTrials.gov