Barley Beta-glucan, Glycemic Control, and Appetite

Summary

Novel barley varieties high in the soluble fiber β-glucan have the capacity to improve population health through improving glycemic control. Sweetened and unsweetened wholegrain barley foods were tested in a randomized, controlled, crossover human clinical trial to assess impact on postprandial appetite and food intake.

Conditions

• Diet, Healthy
• Blood Sugar; High
• Diabetes
• Appetite and General Nutritional Disorders
• Appetitive Behavior

Interventions

OTHER

WR

Unsweetened preload condition: 240 mL white glutinous rice, 250 kcal, 0 g β-glucan

OTHER

LB

Unsweetened preload condition: 240 mL low β-glucan barley, 250 kcal, \~4 g β-glucan

OTHER

MB

Unsweetened preload condition: 240 mL medium β-glucan barley, 250 kcal, \~5 g β-glucan

OTHER

HB

Unsweetened preload condition: 240 mL high β-glucan barley, 250 kcal, \~6 g β-glucan

OTHER

WR+50g HFCS

Sweetened condition with high fructose corn syrup (HFCS): 240 mL white glutinous rice + 50g HFCS, 391 kcal, 0 g β-glucan

OTHER

LB + 50 g HFCS

Sweetened condition with high fructose corn syrup (HFCS): 240 mL low β-glucan barley + 50 g HFCS, 391 kcal, \~4 g β-glucan

OTHER

MB + 50 g HFCS

Sweetened condition with high fructose corn syrup (HFCS): 240 mL medium β-glucan barley + 50 g HFCS, 391 kcal, \~5 g β-glucan

OTHER

HB + 50 g HFCS

Sweetened condition with high fructose corn syrup (HFCS): 240 mL high β-glucan barley + 50 g HFCS, 391 kcal, \~6 g β-glucan

Sponsors & Collaborators

• Washington State University

  lead OTHER

Principal Investigators

• Martine Perrigue, PhD, RDN · Washington State University

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

50 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2019-10-01

Primary Completion

2020-10-31

Completion

2020-10-31

Countries

• United States

Study Locations