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Chronic Cardiovascular and Gut-bacteria Effects of Phenolic Rich Oats in Adults With Above Average Blood Pressure

NCT02847312 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2016-07-28

No results posted yet for this study

Summary

In this proposed human trial, the investigators aim to establish whether 4 weeks of daily consumption of beta-glucan matched meals providing either a high dose or a moderate dose of oat avenanthramides and phenolic acids leads to dose-dependent chronic improvements in markers of CVD risk and gut health relative to an energy matched control intervention in healthy adults with above average blood pressure.

Conditions

  • Healthy

Interventions

OTHER

High avenanthramide, phenolic acid

High avenanthramide and high phenolic acid, matched with energy and insoluable fibre.

OTHER

Low avenanthramide, medium phenolic acid

Low avenanthramide and moderate phenolic acid, matched with energy and insoluable fibre.

OTHER

Control

Control are matched with energy and insoluable fibre.

Sponsors & Collaborators

  • PepsiCo, Inc.

    collaborator INDUSTRY

  • Rothamsted Research

    collaborator UNKNOWN

  • Biotechnology and Biological Sciences Research Council

    collaborator OTHER

  • University of Reading

    lead OTHER

Principal Investigators

  • Jeremy P Spencer, Professor · University of Reading

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
25 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-07-31
Primary Completion
2017-04-30
Completion
2017-04-30

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02847312 on ClinicalTrials.gov