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Absorption, Metabolism and Excretion of Apigenin and Apigenin Glycosides

NCT03526081 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 17

Last updated 2019-05-23

No results posted yet for this study

Summary

Probe dietary intervention study in healthy young adult males to evaluate the concentration of apigenin derived metabolites in plasma and urine after single acute intakes of different apigenin-containing test materials.

Conditions

  • Healthy

Interventions

OTHER

Chamomile Tea

Chamomile Tea in 300mL hot water

OTHER

Parsley based drink

3.2 g dried parsley in 300mL hot water

OTHER

Parsley Yogurt

3.2 g dried parsley in 100g plain yogurt

OTHER

Apigenin

Apigenin capsule mixed with 300mL hot water

OTHER

Parsley-based drink (II)

3.2 g dried parsley in 300mL hot water

Sponsors & Collaborators

  • Mars, Inc.

    collaborator INDUSTRY

  • University of California, Davis

    lead OTHER

Principal Investigators

  • Carl L Keen, PhD · UC Davis

  • Javier I Ottaviani, PhD · Mars, Inc.

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
25 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-01-20
Primary Completion
2016-07-30
Completion
2016-07-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03526081 on ClinicalTrials.gov