Acute Assessment of Platelet Reactivity After the Intake of Oleocanthal
NCT03528603 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 26
Last updated 2024-06-24
Summary
The investigators have previously observed a reduced level of platelet aggregation 2 hours after healthy male individuals were asked to drink extra virgin olive oil (EVOO) that provided a higher level of one specific phenolic known as oleocanthal. This study will help the investigators further determine the effects of oleocanthal-rich EVOO intake on platelet function at 2, 4 and 6 hours after intake with food compared to platelet function in the morning after an overnight fast.
Conditions
- Platelet Aggregation
- Nutritional and Metabolic Disease
- Cardiovascular Diseases
Interventions
- OTHER
-
Oleocanthal-Rich Extra Virgin Olive Oil
Extra Virgin Olive Oil that contains a high level of the phenolic oleocanthal
- OTHER
-
Oleocanthal-low Extra Virgin Olive Oil
Extra Virgin Olive Oil that contains a low level of the phenolic oleocanthal
Sponsors & Collaborators
-
University of California, Davis
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 20 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-04-02
- Primary Completion
- 2023-03-01
- Completion
- 2024-05-31
Countries
- United States
Study Locations
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