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Food Matrix Effect on Flavanol Absorption, Metabolism and Excretion: Methylxanthines

NCT03526107 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2022-10-10

No results posted yet for this study

Summary

Dietary intervention study in healthy young adult males to evaluate concentration of flavanol metabolites in plasma and urine after single acute intakes of methylxanthines.

Conditions

  • Healthy

Interventions

OTHER

CF Control

CF Control: 587 mg of cocoa flavanols, \<1 mg caffeine and \<1 mg theobromine

OTHER

CF-Theobromine

CF-Theobromine: 575 mg of cocoa flavanols, 11 mg caffeine and 93 mg theobromine

OTHER

CF-Caffeine

CF-Caffeine: 587 mg of cocoa flavanols, 112 mg caffeine and \<1 mg theobromine

Sponsors & Collaborators

  • Mars, Inc.

    collaborator INDUSTRY

  • University of California, Davis

    lead OTHER

Principal Investigators

  • Carl L Keen, PhD · Mars, Inc.

  • Javier I Ottaviani, PhD · Mars, Inc.

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
25 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-02-16
Primary Completion
2017-05-31
Completion
2017-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03526107 on ClinicalTrials.gov