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Colonic Propionate, Appetite, and Weight Loss

NCT03322514 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2019-11-20

Study results available
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Summary

The current protocol aims to investigate the impact of the propionate ester in conjugation with restricted diet on appetite and weight loss.

Conditions

  • Healthy Obesity, Metabolically
  • Appetite Regulation

Interventions

DIETARY_SUPPLEMENT

Inulin-Propionate Esters

Inulin (β(2-1) linked polymer of fructose) carrier with an ester linked to propionate (propionate ester). Thus, propionate is only released when the carrier molecule inulin is fermented by colon microflora.

DIETARY_SUPPLEMENT

Inulin

Inulin

Sponsors & Collaborators

  • University of Glasgow

    collaborator OTHER

  • Imperial College London

    lead OTHER

Principal Investigators

  • Gary Frost · Dietitian; PhD in Nutrition; Professor of nutrition and dietetics

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-03-29
Primary Completion
2017-11-11
Completion
2017-11-11

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03322514 on ClinicalTrials.gov