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Eating Disinhibition and Vagal Tone and the Postprandial Response to Glycaemic Load

NCT02827318 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 66

Last updated 2016-07-11

No results posted yet for this study

Summary

Reducing the glycaemic load (GL) of the diet may benefit appetite control but its utility is complicated by psychological influences on eating. Disinhibited behaviour, a risk factor for overconsumption, is characterized by reduced prefrontal cortex activity, which in turn directly modulates vagal tone; a phenomenon inversely associated with blood glucose (BG) and insulin levels. This double blind randomised controlled trial explores the influence of disinhibited eating and vagal tone (heart rate variability) on the postprandial response to GL and hunger.

Conditions

  • Hunger

Interventions

DIETARY_SUPPLEMENT

Isomaltulose

75g Isomaltulose (low glycaemic load intervention)

DIETARY_SUPPLEMENT

Glucose

75g Glucose (high glycaemic load intervention)

DIETARY_SUPPLEMENT

Sweetened water

Sweetened water will be used as a control

Sponsors & Collaborators

  • Swansea University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2015-12-31
Completion
2015-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02827318 on ClinicalTrials.gov