MedTrace Logo

Effect of Non-essential Amino Acids on Protein Requirements for Endurance Athletes

NCT02874638 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 7

Last updated 2019-04-01

No results posted yet for this study

Summary

Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).

The biological value of protein depends on its amino acid composition. Essential amino acids are believed to have main role on whole body protein metabolism. However, it remains to be determined what role non-essential amino acids (NEAA) may have in regulating protein metabolism and contributing to the increased protein requirements after endurance exercise.

The indicator amino acid oxidation (IAAO) method has clarified the individual amino acid requirement in children, normal healthy adult and clinical populations. However, the IAAO method has never been utilized for assessing the effect of NEAA on protein requirements after endurance exercise.

The objective of the current study is to investigate the importance of NEAA for endurance-trained male subjects.

Conditions

  • Increased Metabolic Requirement
  • Healthy

Interventions

DIETARY_SUPPLEMENT

BASE egg protein

0.8 g/kg/d of protein provided as crystalline amino acid modeled after egg protein

DIETARY_SUPPLEMENT

BCAA-enriched egg protein

BCAA-enriched egg protein provided as crystalline amino acid.

DIETARY_SUPPLEMENT

small amount of essential amino acids

essential amino acids modeled after egg protein, provided as crystalline amino acid, which is equivalent to the amount of essential amino acid in BASE egg protein

DIETARY_SUPPLEMENT

large amount of essential amino acids

essential amino acids modeled after egg protein, provided as crystalline amino acid, which is equivalent to the amount of amino acid in BCAA-enriched egg protein

Sponsors & Collaborators

  • Ajinomoto Co., Inc.

    collaborator INDUSTRY

  • University of Toronto

    lead OTHER

Principal Investigators

  • Daniel Moore, Ph.D. · University of Toronto

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-09-30
Primary Completion
2017-08-31
Completion
2017-12-31

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02874638 on ClinicalTrials.gov