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Influence of Sex and Training on de Novo Muscle Protein Synthesis

NCT04887883 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2021-05-14

No results posted yet for this study

Summary

Acute exercise increases the incorporation of dietary amino acids into de novo myofibrillar proteins after a single meal in controlled laboratory studies in males. It is unclear if this extends to free-living settings or is influenced by training or sex. Over 24 h in a free-living setting, the investigators determined the effect of training status and sex on dietary phenylalanine incorporation into contractile myofibrillar and noncontractile sarcoplasmic proteins after exercise.

Conditions

  • Amino Acids
  • Dietary Protein
  • Sex
  • Resistance Exercise

Interventions

BEHAVIORAL

Resistance exercise

Participants performed 8 weeks of resistance training and muscle biopsies were taken before and 24 h before and after the program.

Sponsors & Collaborators

  • Natural Sciences and Engineering Research Council, Canada

    collaborator OTHER

  • University of Toronto

    lead OTHER

Principal Investigators

  • Daniel Moore, PhD · University of Toronto

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-01
Primary Completion
2019-09-01
Completion
2019-09-01

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04887883 on ClinicalTrials.gov