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Modulation of Muscle Protein Metabolism by Essential Amino Acids

NCT01890369 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2014-01-17

No results posted yet for this study

Summary

The investigators plan to explore the ability of amino acids, the building blocks of proteins in our bodies and in the food we eat, to stimulate muscles to grow and stay strong. The investigators will investigate how rapidly after one meal the human body is ready to make use of a second meal and look at the molecular mechanisms underlying this. The investigators will look at these phenomena in older men as this group is known to be subject to a gradual loss of muscle mass and strength.

Conditions

  • Old Age

Interventions

DIETARY_SUPPLEMENT

15g Mixed Essential Amino Acids

Dissolved in 250ml water.

DIETARY_SUPPLEMENT

3g Leucine

Dissolved in 250ml water.

DIETARY_SUPPLEMENT

15g Mixed Essential Amino Acid REFEED

Dissolved in 250ml water.

Sponsors & Collaborators

  • Ajinomoto Co., Inc.

    collaborator INDUSTRY

  • University of Nottingham

    lead OTHER

Principal Investigators

  • Philip J Atherton, PhD · University of Nottingham

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Max Age
75 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-04-30
Primary Completion
2014-06-30
Completion
2014-07-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01890369 on ClinicalTrials.gov