Effect of Branched-chain Amino Acid Supplementation on Muscle Damage

NCT03766815 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 78

Last updated 2019-10-02

No results posted yet for this study

Summary

Seventy-eight recreational athletes who never resistance trained will be randomly assigned into three groups of twenty-six. Branched-chain amino acid will be supplemented for 18days at 0, 200 or 400 mg/body weight(kg)/day in jelly. Participants will be asked to perform elbow flexions on the 12th day of supplementation. Maximum voluntary contractions will be measured before, during and after the supplementation period to compare the effects of different doses of branched-chain amino acid has on muscle damage markers.

Conditions

  • Muscle Damage

Interventions

DIETARY_SUPPLEMENT

BCAA 200mg/kg/day

BCAA supplement based on 200mg/kg/day for 18 days.

DIETARY_SUPPLEMENT

Placebo

Fiber supplement jelly for 18 days.

DIETARY_SUPPLEMENT

BCAA 400mg/kg/day

BCAA supplement based on 400mg/kg/day for 18 days.

BEHAVIORAL

Muscle damaging exercise

Participants will be asked to perform muscle damaging elbow eccentric contraction exercise at 120% of 1RM for three sets of 15 repetitions with the dominant arm at maximal effort on a Biodex machine with a 3 minute rest period between each set.

Sponsors & Collaborators

  • Western University, Canada

    lead OTHER

Principal Investigators

  • Peter Lemon, PhD · Western University

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-10-01
Primary Completion
2019-12-31
Completion
2019-12-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03766815 on ClinicalTrials.gov