Oat Phenolics Bioavailability

NCT02574039 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 7

Last updated 2015-10-12

No results posted yet for this study

Summary

A diet rich in whole grain is inversely associated with cardiovascular disease risk and this benefit could be partly attributed to the phenolic acid content of whole grains. The exact absorption, metabolism and excretion of whole grain phenolic acids, however, is not fully understood. In a small human intervention trial, the investigators will investigate to what extent phenolic acids from whole grain oats are absorbed, excreted in urine and how they are metabolised.

Conditions

  • Healthy

Interventions

DIETARY_SUPPLEMENT

Oat bran

66g oat bran made up in 350ml skimmed milk

DIETARY_SUPPLEMENT

refined grain

refined grain product and 350ml skimmed milk

Sponsors & Collaborators

  • PepsiCo Global R&D

    collaborator INDUSTRY
  • University of Reading

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
25 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-07-31
Primary Completion
2015-10-31
Completion
2015-10-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02574039 on ClinicalTrials.gov