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The Effect of the Glycemic Load of Meals on the Cognition and Mood of Older Adults

NCT01842022 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 155

Last updated 2014-12-11

No results posted yet for this study

Summary

A lower rather than a higher glycemic load (GL) meal has been shown to benefit cognition and mood, however, the data in older adults and those most prone to cognitive dysfunction, is limited and conflicting. One explanation is that the GL of a meal may interact with a person's pre-existing glucose tolerance (GT).

As older adults have a higher incidence of glucose tolerance and are more likely to experience memory problems the present study considers the interaction between the GL of meal in those with better or poorer GT.

The population studied will not have a history of diabetes or dementia. A battery of cognitive tests will be administered after meals sweetened with one of three sugars known to vary in the rate that they release glucose into the blood stream.

Conditions

Interventions

DIETARY_SUPPLEMENT

Isomaltulose

Isomaltulose sweetened meal will be given to each of four groups who differ in their glucose tolerance

DIETARY_SUPPLEMENT

Sucrose

Sucrose sweetened meal will be given to each of four groups who differ in their glucose tolerance

DIETARY_SUPPLEMENT

Glucose

Glucose sweetened meal will be given to each of four groups who differ in their glucose tolerance

Sponsors & Collaborators

  • Swansea University

    lead OTHER

Principal Investigators

  • David Benton, DSc · Swansea University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-09-30
Primary Completion
2013-05-31
Completion
2013-09-30

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01842022 on ClinicalTrials.gov