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Cardiovascular Health Effects of Flavanol Rich Chocolate

NCT01308892 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 44

Last updated 2011-06-17

No results posted yet for this study

Summary

In the CHOC study the investigators will examine the effect of chocolate flavanols on vascular function, inflammation, oxidative stress and markers of endothelial function. The effects of both acute consumption and prolonged consumption will be studied. The secondary objectives are to investigate if daily intake of chocolate flavanols for 4 weeks will improve the response to a high fat/high energy challenge.

Conditions

  • Endothelial Dysfunction

Interventions

DIETARY_SUPPLEMENT

High flavanol chocolate

chocolate high in flavanols

DIETARY_SUPPLEMENT

Low flavanol chocolate

chocolate low in flavanols

DIETARY_SUPPLEMENT

High fat challenge

Milkshake with 95g fat

Sponsors & Collaborators

  • Top Institute Food and Nutrition

    collaborator OTHER

  • Wageningen University

    lead OTHER

Principal Investigators

  • Michael Müller, Prof.Dr · Chair Department of human nutrition NMG group

Study Design

Allocation
RANDOMIZED
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
45 Years
Max Age
70 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-01-31
Primary Completion
2011-06-30
Completion
2011-06-30

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01308892 on ClinicalTrials.gov