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Effects of Chocolate in Patients With Chronic Heart Failure

NCT00538941 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2009-10-28

No results posted yet for this study

Summary

The aim of the present study is to investigate whether in patients with chronic heart failure endothelial dysfunction and baroreceptor function is altered by ingestion of a flavonoid-rich dark chocolate in comparison to placebo chocolate (Nestlé Placebo Chocolate) on top of standard medication.

Moreover, we will evaluate the effect of chocolate on oxidative stress, platelet adhesion as well as systemic inflammatory response such as C-reactive protein and pro-inflammatory cytokines in patients with chronic heart failure.

Conditions

Interventions

DIETARY_SUPPLEMENT

Nestlé Noir intense 40 grx2

daily intake of 40gr chocolate (Nestlé Noir intense or Nestlé Placebo Chocolate) in the morning and 40gr chocolate in the evening.

DIETARY_SUPPLEMENT

Nestlé Placebo Chocolate 40 grx2

Nestlé Placebo Chocolate 40 gr in the morning and 40gr chocolate in the evening.

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Georg Noll, MD · Cardiovascular Center, University Hospital Zurich, Zurich, Switzerland

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-11-30
Primary Completion
2009-10-31
Completion
2009-10-31

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00538941 on ClinicalTrials.gov