MedTrace Logo

Effect of Fibre Products on Appetite and Weight

NCT00750438 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2019-11-19

Study results available
· View outcomes & findings →

Summary

This study explores the nutritional effects of fibre. Short chain fatty acid(SCFA), such as propionate, are produced through the fermentation of fibre in the bowel. SCFA are thought to have direct beneficial effects on the gut, appetite, weight and fat distribution. This study will look into these effects by conducting a dose finding study and then a randomised controlled study using healthy human volunteers.

Conditions

Interventions

DIETARY_SUPPLEMENT

Propionate ester

The subject will take propionate ester at the dose specified by the dose finding study, three times a day for 24 weeks

DIETARY_SUPPLEMENT

Inulin

The subjects in this group will take inulin at a comparable dose, three times a day for 24 weeks

DIETARY_SUPPLEMENT

Cellulose

The subjects in this group will take the non fermentable carbohydrate, cellulose, at a comparable dose for 24 weeks.

Sponsors & Collaborators

  • Imperial College London

    lead OTHER

Principal Investigators

  • Gary Frost, PhD · Imperial College London

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-09-30
Primary Completion
2012-07-31
Completion
2012-10-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00750438 on ClinicalTrials.gov