MedTrace Logo

Determination of the Optimal Nutrient Mix to Acutely Increase Plasma Ketones

NCT06511206 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 11

Last updated 2025-04-04

No results posted yet for this study

Summary

This study will be performed to determine the optimal nutrient mix (predominantly based on medium-chain triglycerides (MCTs)) to induce a mild ketogenic state in healthy older (60-80y), overweight/obese (BMI: 25-35 kg/m2) individuals. Since the aim is to induce a mild ketogenic state, a 25g MCT-based nutrient mix, a 25g MCT-based nutrient mix + cofactors, or a non-ketogenic control will be compared.

Conditions

  • Overweight and Obesity

Interventions

DIETARY_SUPPLEMENT

25g MCT-based nutrient mix

The 25g MCT-based nutrient mix will be consumed two hours after breakfast.

DIETARY_SUPPLEMENT

25g MCT-based nutrient mix + cofactors

The 25g MCT-based nutrient mix + cofactors will be consumed two hours after breakfast.

DIETARY_SUPPLEMENT

non-ketogenic control

The non-ketogenic control will be consumed two hours after breakfast.

Sponsors & Collaborators

  • Maastricht University Medical Center

    lead OTHER

Principal Investigators

  • Joris Hoeks, Dr. · Maastricht University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
60 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-08-08
Primary Completion
2025-03-27
Completion
2025-03-31

Countries

  • Netherlands

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06511206 on ClinicalTrials.gov