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Scavenging of Reactive Carbonyl Species by Dietary Flavonoids in Humans

NCT05773794 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2025-05-25

Study results available
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Summary

This is an interventional study to investigate the formation and pharmacokinetics of reactive carbonyl species adducts of dietary polyphenols (soymilk, green tea, and blueberry) in humans after a single dose of dietary flavonoids.

Conditions

  • Human Health
  • Reactive Carbonyl Species
  • Polyphenols

Interventions

DIETARY_SUPPLEMENT

Soymilk, green tea, or blueberry

One dose of soymilk, green tea, or blueberry blends (460mL) with breakfast.

DIETARY_SUPPLEMENT

Control group

Breakfast with milk or water, without soymilk, green tea, or blueberry blends.

Sponsors & Collaborators

  • North Carolina Agriculture & Technical State University

    lead OTHER

Principal Investigators

  • Shengmin Sang, PhD · NC A&T State University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
25 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-06
Primary Completion
2023-12-19
Completion
2023-12-19

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05773794 on ClinicalTrials.gov