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Effect of Pterostilbene on Cholesterol, Blood Pressure and Oxidative Stress

NCT01267227 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2018-01-10

Study results available
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Summary

Pterostilbene is one of several stilbenes found in certain berries, particularly blueberries, that have demonstrated pre-clinical benefit to cholesterol, blood pressure, and oxidative stress. The purpose of this study is to evaluate whether pterostilbene will help control cholesterol and blood pressure, as well as improve markers for oxidative stress in patients with dyslipidemia meeting inclusion criteria. The investigators also want to look at the safety of pterostilbene in these patients.

Conditions

Interventions

DRUG

Pterostilbene 50 mg twice daily

Pterostilbene 50 mg twice by mouth daily for 6 to 8 weeks

DRUG

Placebo

Matching placebo by mouth twice daily for 6 to 8 weeks

DRUG

Grape Extract

Grape extract 100 mg twice daily for 6-8 weeks

DRUG

Pterostilbene 125 mg twice daily

Pterostilbene 125 mg twice daily for 6-8 weeks

Sponsors & Collaborators

  • University of Mississippi Medical Center

    lead OTHER

Principal Investigators

  • Daniel M Riche, Pharm.D. · University of Mississsippi

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
88 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-12-31
Primary Completion
2012-02-29
Completion
2012-02-29

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01267227 on ClinicalTrials.gov