Imaging the Pathogenesis of Cerebral Small Vessel Disease
NCT05703386 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2026-03-03
Summary
Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter hyperintensities (WMH) on MRI. The goal of this study it to recruit and follow individuals at risk for WMH progression and use serial MRI scanning to gain insights into the pathogenesis of CSVD.
Conditions
- Ischemic Stroke
- Hypertension
- Hyperlipidemias
- Diabetes
Sponsors & Collaborators
-
National Institute of Neurological Disorders and Stroke (NINDS)
collaborator NIH - lead OTHER
Principal Investigators
-
Richard Leigh, MD · Johns Hopkins University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-11-08
- Primary Completion
- 2027-03-31
- Completion
- 2027-03-31
Countries
- United States
Study Locations
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