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Imaging Studies in Corticobasal Syndrome

NCT07000851 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2025-07-07

No results posted yet for this study

Summary

The primary goal of this study is to investigate inflammation and white matter damage in corticobasal syndrome and determine whether these processes are related to each other. The investigator's will address our goal by using neuroimaging and blood plasma biomarkers, as well as molecular pathology.

Conditions

  • Cortico Basal Degeneration
  • Corticobasal Syndrome
  • Corticobasal Syndrome(CBS)
  • Corticobasal Degeneration
  • Corticobasal Degeneration (CBD)
  • Corticobasal Syndrome (CBS)

Interventions

DIAGNOSTIC_TEST

C-11 ER176 Radiotracer

PET scan looking for inflammation

DIAGNOSTIC_TEST

C-11 PiB

PET scan looking for amyloid protein

DIAGNOSTIC_TEST

AV1451 Tau

Pet scan looking for Tau protein

Sponsors & Collaborators

  • National Institute on Aging (NIA)

    collaborator NIH

  • Jennifer Whitwell

    lead OTHER

Principal Investigators

  • Jennifer Whitwell, Ph.D. · Mayo Clinic

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-06-25
Primary Completion
2030-03-30
Completion
2031-03-30
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07000851 on ClinicalTrials.gov