MedTrace Logo

The Impact of Leg Immobilization on Postabsorptive and Postprandial Muscle Protein Breakdown in Healthy Young Males

NCT03934632 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2023-03-22

No results posted yet for this study

Summary

The present study will seek the quantify the simultaneous muscle protein synthesis and breakdown response with and without amino acid provision in humans following 2 days of immobilisation.

Conditions

  • Healthy

Interventions

OTHER

Postabsorptive

Saline will be infused to mimic postabsorptive circulating amino acid concentrations

OTHER

Postprandial

An amino acid infusate will be administered to mimic postprandial circulating amino acid concentrations

PROCEDURE

Immobilisation

One leg will undergo 2 days immobilisation prior to the test day

Sponsors & Collaborators

  • University of Exeter

    lead OTHER

Principal Investigators

  • Marlou Dirks, PhD · University of Exeter

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-04-15
Primary Completion
2020-03-17
Completion
2023-01-09

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03934632 on ClinicalTrials.gov