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Oral Infections: Dietary Regulation of Local and Systemic Inflammatory Responses

NCT00632957 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 126

Last updated 2011-04-12

No results posted yet for this study

Summary

The purpose of this study is to test the hypothesis that dietary n-3 PUFA will have a beneficial effect on systemic and local markers of inflammation when combined with traditional, non-surgical periodontal therapy.

Conditions

  • Periodontal Attachment Loss

Interventions

DIETARY_SUPPLEMENT

Omega-3 Fatty acid (with SRP or OHI)

1000mg capsules three times daily, duration 28 weeks.

DIETARY_SUPPLEMENT

Placebo

corn/soybean oil capsules 1g/three times daily

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • National Center for Research Resources (NCRR)

    collaborator NIH

  • University of Kentucky

    lead OTHER

Principal Investigators

  • Dolph R. Dawson, DMD,MS · University of Kentucky College of Dentistry

  • Jeff L. Ebersole, Ph.D · University of Kentucky College of Dentistry

  • M J Novak, Ph.D · University of Kentucky College of Dentistry

  • Gilbert A. Boissonneault, Ph.D · University of Kentucky Division of Clinical Nutrition

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2004-09-30
Primary Completion
2009-05-31
Completion
2009-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00632957 on ClinicalTrials.gov