Pharmacogenetics Study on the Effects of Anesthetic Drugs on Circulatory Function
NCT03839186 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 223
Last updated 2022-03-02
Summary
This study intends to study the effects of anesthetics on Circulatory Function Genomics and find the anesthetic effects in pharmacodynamics, pharmacokinetics, drug receptor or target DNA level differences, further guiding individual treatment in clinic, promoting the development of precision the medicine.The anesthesia medication during perioperative period is more and more accurate,reasonable and safe, so as to improve the satisfaction of the patients and their families in the perioperative period, to ensure the safety of patients.
Conditions
- Drug Reaction
- Anesthetic
- Hemodynamic Rebound
- Gene
Sponsors & Collaborators
-
Xiangya Hospital of Central South University
lead OTHER
Principal Investigators
-
e wang, doctor · Xiangya Hospital of Central South University
Eligibility
- Min Age
- 20 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-08-31
- Primary Completion
- 2018-12-31
- Completion
- 2019-04-30
Countries
- China
Study Locations
More Related Trials
-
Anesthetic Methods and Gene Expression Profile
NCT03585647 ·Status: COMPLETED
-
Study on the Effect of Target-controlled Infusion for General Anesthesia in Cardiac Surgery
NCT06012955 ·Status: UNKNOWN
-
To Study the Pharmacokinetic and Cardiovascular Effects of Propofol With Respect to Pharmacogenetics in Pakistani Population
NCT05383534 ·Status: COMPLETED
-
A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia
NCT06334549 ·Status: RECRUITING ·Phase: PHASE4
-
MicroRNA Mediates Volatile Anesthetics Preconditioning Induced Artery Protection
NCT02678650 ·Status: UNKNOWN ·Phase: PHASE4
-
The Effect of the ALDH2 Gene Polymorphism on the Propofol Potency for Inducing Loss of Consciousness
NCT03762538 ·Status: UNKNOWN
-
Effects on Immun System of Anesthesia
NCT02056561 ·Status: COMPLETED
-
Observation of Propofol Titration at Different Speeds
NCT04595591 ·Status: COMPLETED ·Phase: NA
-
Hemodynamic Changes After Anesthesia With Propofol: Study of Biomarkers
NCT02442232 ·Status: COMPLETED
-
Pharmacogenetics of Propofol and Depth of Anesthesia
NCT01029379 ·Status: COMPLETED
-
Effect of Neoadjuvant Chemotherapy on Cardiac Function of Perioperative Patients With Breast Cancer and New Strategies for Anesthesia
NCT06497660 ·Status: RECRUITING ·Phase: PHASE4
-
The Effects of Remimazolam on Cerebral Blood Flow Following General Anesthesia Induction
NCT07303985 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Correlation Between the Debilitating State of the Elderly and Propofol Sensitivity
NCT06870357 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Perioperative Pharmacogenomic Testing
NCT05063838 ·Status: UNKNOWN ·Phase: NA
-
Changes in Autonomic Nervous Activity and Blood Pressure After Anesthesia Induction: Remimazolam Versus Propofol
NCT05635201 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia
NCT05954832 ·Status: RECRUITING
-
The Effect of Anesthesia on Perioperative Muscle Weakness and Neuro-endocrine Stress Response
NCT03600454 ·Status: COMPLETED ·Phase: NA
-
Anesthesia Quality Control Indicators of 6 Provinces in Central China
NCT05926323 ·Status: WITHDRAWN
-
Pharmacokinetics and Pharmacodynamics of Rocuronium in Closed-Loop Infusion System
NCT02364934 ·Status: UNKNOWN
-
The Effects of General Anesthesia on Microcirculation of Central and Peripheral Soft Tissue: a Comparison of Inhalational and Intravenous Anesthetics
NCT02530632 ·Status: UNKNOWN ·Phase: NA
-
The Effect of Intravenous Lidocaine on Postoperative Cognitive Function in Elderly Patients
NCT05502705 ·Status: UNKNOWN ·Phase: NA
-
Optimal Lidocaine Propofol Mixture for Painless Induction of Anesthesia
NCT05898061 ·Status: UNKNOWN
-
Hemodynamic Changes and Propofol Pharmacokinetic Variation During Anesthesia Induction and Knee-chest Positioning
NCT03961958 ·Status: COMPLETED ·Phase: NA
-
Using Preoperative Anxiety Score to Determine the Total Dose of Butorphanol for Sedation
NCT03810391 ·Status: COMPLETED ·Phase: PHASE2
-
Application of the Propofol Precise Infusion Model
NCT05158426 ·Status: COMPLETED