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A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia

NCT06334549 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 180

Last updated 2024-11-06

No results posted yet for this study

Summary

The purpose of this study is to investigate whether norepinephrine(N), phenylephrine(P) or ephedrine(E) have different effect on cerebral oxygenation in abdominal surgery with propofol or sevoflurane.

Conditions

  • Hypotension Drug-Induced

Interventions

DRUG

Ephedrine-P

after induction of anesthesia, use total intravenous anesthesia maintained with propofol

DRUG

Phenylephrine-P

after induction of anesthesia, use total intravenous anesthesia maintained with propofol

DRUG

Norepinephrine-P

after induction of anesthesia, use total intravenous anesthesia maintained with propofol

DRUG

Ephedrine-S

after induction of anesthesia, use inhalation anesthesia maintained with sevoflurane

DRUG

Phenylephrine-S

after induction of anesthesia, use inhalation anesthesia maintained with sevoflurane

DRUG

Norepinephrine-S

after induction of anesthesia, use inhalation anesthesia maintained with sevoflurane

Sponsors & Collaborators

  • Dalian Municipal Central Hospital

    lead OTHER

Principal Investigators

  • Hong Fang, MD · Dalian Municipal Central Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-03-05
Primary Completion
2025-12-05
Completion
2025-12-05

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06334549 on ClinicalTrials.gov