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MicroRNA Mediates Volatile Anesthetics Preconditioning Induced Artery Protection

NCT02678650 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2016-02-10

No results posted yet for this study

Summary

It has been reported that volatile anesthetics preconditioning mediates protection of organ via microRNA. We want to study on the effects of isoflurane preconditioning on expression of microRNA and mRNA in the specimens of internal mammary artery and ascending aorta.

Conditions

  • Coronary Artery Bypass Graft Triple Vessel

Interventions

DRUG

volatile anesthetics(isoflurane)

volatile anesthetics wash-in / wash-out operation

DRUG

propofol intravenous anesthesia

propofol infusion 3-5μg / kg / h

Sponsors & Collaborators

  • Liang Zhang

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-01-31
Primary Completion
2017-01-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02678650 on ClinicalTrials.gov