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Optimal Lidocaine Propofol Mixture for Painless Induction of Anesthesia

NCT05898061 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2023-06-12

No results posted yet for this study

Summary

This research will be carried out in order to determine the optimal lidocaine dose in propofol lidocaine mixture to prevent pain on propofol injection during induction of general anesthesia using a modified Dixon's up-and-down method. Patients \& methods: Include assessment of severity of pain on propofol injection using seven doses of lidocaine in lidocaine propofol mixture in ASA I\&II patients aged 18-60 years with exclusion of patients with history of drug allergy, hepatic or renal impairment, cardiac problems, neurologic deficits or psychiatric disorders.

The primary outcome will be pain scale during injection and volume of propofol-lidocaine mixture used. Secondary outcome will be increase in heart rate and/or hand or forearm withdrawal during injection, patient satisfaction, demographic data, type and duration of surgery, Time for unconsciousness.

Aim of the work: To determine the Minimal effective dose of lidocaine in propofol lidocaine mixture to achieve painless induction of anesthesia using propofol.

Conditions

  • Pain, During Injection of Propofol for Induction of Anesthesia

Sponsors & Collaborators

  • Sohag University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-03-01
Primary Completion
2023-12-01
Completion
2023-12-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05898061 on ClinicalTrials.gov