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Application of the Propofol Precise Infusion Model

NCT05158426 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2021-12-15

No results posted yet for this study

Summary

Propofol is one of the most commonly used anesthetics in the world. However, the dose-response of propofol was remarkable variety. Herein, this study aims to investigate the possible association of gene polymorphism and propofol susceptibility, and to research more precise infusion model of this drug.

Conditions

  • Propofol Overdose of Undetermined Intent

Interventions

DRUG

Propofol

anesthesia induction is initiated with intravenous infusion propofol at 1.5µg/ml, and increased 0.5µg/ml every 3min until OAA/S score 0.

Sponsors & Collaborators

  • West China Hospital

    lead OTHER

Principal Investigators

  • Weimin Li · West China Hospital

  • lin Zhang · West China Hospital

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-20
Primary Completion
2021-11-15
Completion
2021-11-18
FDA Drug
Yes

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05158426 on ClinicalTrials.gov