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Visualizing Vascular Mechanisms of Salt Sensitivity

NCT03696433 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 19

Last updated 2026-04-23

Study results available
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Summary

This study aims to assess the salt sensitive blood pressure response to dietary salt load compared with radiological markers of salt handling.

Conditions

  • Obesity
  • Cardiovascular Risk Factor
  • Salt; Excess

Interventions

DIETARY_SUPPLEMENT

Low-salt diet

The low-salt diet (7 days) will consist of meals, snacks and water provided by Vanderbilt's metabolic kitchen.

DIETARY_SUPPLEMENT

High-salt diet

The high-salt diet (7 days) consists of each subject's typical diet, supplemented each day with 2 bullion broth packets, which will be provided to the subject by the study staff.

Sponsors & Collaborators

Principal Investigators

  • Rachelle Crescenzi, PhD · Department of Radiology, Vanderbilt University Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-02-01
Primary Completion
2022-11-04
Completion
2022-11-04

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03696433 on ClinicalTrials.gov