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A Biomarker to Detect Salt Sensitivity

NCT03147170 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2019-04-18

No results posted yet for this study

Summary

The investigators are proposing that individuals with elevated levels of NT-proBNP are resistant to natriuretic peptides and are unable to handle sodium loads and maintain optimal blood pressure values.The investigators will test this hypothesis by comparing the blood pressure response to low and high salt diets in individuals with pre- or hypertension and who have normal or elevated levels of NT-proBNP. The investigators expect that blood pressure values in those with normal levels of NT-proBNP will not change with high salt diets, whereas, in those with elevated levels of NT-proBNP, blood pressure values will increase significantly when exposed to high salt diets.

Conditions

  • Hypertension Uncomplicated
  • Pre Hypertension

Interventions

DIAGNOSTIC_TEST

High and low salt diets

Effects of high and low salt diets on blood pressure in individuals with normal and elevated levels of NT-proBNP

Sponsors & Collaborators

Principal Investigators

  • Otto A Sanchez, MD PhD · University of Minnesota

Eligibility

Min Age
30 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-01-01
Primary Completion
2018-06-30
Completion
2018-12-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03147170 on ClinicalTrials.gov