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Effects of Acute Dietary Sodium on Cerebrovascular Reactivity and Blood Pressure Reactivity

NCT03564262 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 37

Last updated 2020-09-22

No results posted yet for this study

Summary

Americans eat more salt than is recommended by the American Heart Association. This is important because consuming a high-salt diet is associated with an increased risk of cardiovascular events, like strokes and heart attacks. In fact, consuming one high-salt meal temporarily reduces blood vessel function and it is not uncommon for Americans to consume high-salt meals. Therefore, our laboratory is interested in determining if a single high-salt meal affects 1) brain blood vessel function at rest and 2) blood pressure responses during exercise.

Conditions

  • Blood Pressure
  • Cerebrovascular Reactivity

Interventions

OTHER

Low Sodium Meal (138 mg sodium)

One Low Sodium Meal

OTHER

High Sodium Meal (1,495 mg sodium)

One High Sodium Meal

Sponsors & Collaborators

  • University of Delaware

    lead OTHER

Principal Investigators

  • William B Farquhar, PhD · University of Delaware

  • Kamila U Migdal, BS · University of Delaware

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-05-01
Primary Completion
2020-06-01
Completion
2020-06-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03564262 on ClinicalTrials.gov