Cardiovascular Diseases

Disease

Related News

CRISPR Therapeutics Reports $581.6M Loss, Advances Gene Editing Pipeline

CRISPR Therapeutics reported a $581.6 million net loss in 2025 with revenue of just $3.5 million, while continuing to advance its gene-editing pipeline including the approved CASGEVY therapy and next-generation CAR T cell programs. The company maintains strategic partnerships and expects current funds to support operations for at least 24 months.

Regional Disparities in Clinical Trial Risks and Representation Highlight Global Challenges

Analysis of 585 clinical trials reveals region is the primary driver of risk variation, with North America showing 29% higher screen failure rates. Heart failure trials show severe underrepresentation, with only 14.5% of participants from outside Europe and North America despite Asia having 50% of global heart failure cases. Central monitoring methods and representativeness indices are proposed to address these disparities.

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Dietary Nitrate and Nitrite Intake and Phosphate Biomarkers and Risk of Chronic Diseases

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Senescence in Myocardial Infarction

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