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Whey vs Casein to Combat Post-inflammatory Protein and Muscle Waste in Acute Disease

NCT03319550 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2019-04-25

No results posted yet for this study

Summary

This study compares three different protein supplements (casein, whey and leucine-enriched whey) and their effect on post-inflammatory muscle waste in a model of acute disease. Each test person will undergo all three interventions.

It is believed that leucine is the primary driver of muscle protein synthesis and therefore we hypothesize that leucine-enriched whey and whey are superior to casein in combating post-inflammatory muscle waste, because of its higher leucine content (16%, 11% and 9% leucine, respectively).

Conditions

  • Muscle Protein Synthesis
  • Endotoxemia
  • Nutrition
  • Milk Protein
  • Metabolism
  • Whey
  • Casein

Interventions

DIETARY_SUPPLEMENT

Casein

see experimental description

DIETARY_SUPPLEMENT

Whey

see experimental description

DIETARY_SUPPLEMENT

Leucine-enriched whey

see experimental description

Sponsors & Collaborators

  • Arla Food for Health

    collaborator UNKNOWN

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Niels Moeller, Professor · Institute for clinical Medicine

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-12-07
Primary Completion
2018-09-19
Completion
2018-09-19

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03319550 on ClinicalTrials.gov