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Comparative Effects of Variable Pressure Support, NAVA and PAV

NCT02499276 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2015-12-29

No results posted yet for this study

Summary

Experimental animal data suggest that increasing breathing pattern variability in mechanical ventilation could be beneficial. Variable ventilation can be induced through the following modes: Neurally Adjust Ventilatory Assist (NAVA), Proportional Assist Ventilation (PAV) and Variable-Pressure Support Ventilation (V-PSV). These modes have not yet been compared to each other. Pilot observations in our department suggest a feasibility in patients.

The objectives of the study are to compare the impact of PSV, NAVA, PAV and V-PSV on the variability of the breathing pattern, patient-ventilator asynchrony, risk of lung overdistension, gas exchange, and repartition of ventilation.

Conditions

Interventions

DEVICE

PSV, NAVA, PAV, Variable-PSV

Each patient enrolled in the study will be ventilated in all the following modes: PSV, NAVA, PAV and variable PSV

Sponsors & Collaborators

  • Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil

    lead OTHER

Principal Investigators

  • Alexandre Demoule, MD, PHD · Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-05-31
Primary Completion
2015-12-31
Completion
2015-12-31

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02499276 on ClinicalTrials.gov