Respiratory failure is a serious condition in which the body cannot adequately oxygenate blood and/or remove carbon dioxide. It can present as hypoxemic or hypercapnic respiratory failure and may be fatal without prompt treatment.
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The FDA has placed a partial hold on U.S. enrollment in a Phase 2 trial of del-desiran for myotonic dystrophy type 1, citing preclinical mouse data showing blood pressure drops not seen in humans, following a serious adverse event in earlier testing.
The FDA approved Zycubo (copper histidinate) on January 13, 2026, as the first treatment for Menkes disease in pediatric patients, following resolution of manufacturing compliance concerns that led to an initial rejection in September 2025.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07542093 |
Bedside Lung Ultrasound to Monitor Lung Recruitment in Obese Patients |
NOT_YET_RECRUITING | |
| NCT07536750 |
Comparison of the Efficacy and Safety of Ciprofol Versus Propofol for Sedation in ICU Patients Undergoing Non-Invasive Ventilation |
RECRUITING | |
| NCT07522450 |
Benefit of Sleep Quality Monitoring by EEG in ICU |
RECRUITING | |
| NCT07521254 |
Noninvasive Technique and High Flow Nasal Oxygen in Respiratory Failure |
RECRUITING | NA |
| NCT07518862 |
Heart Rate VAriability as a MaRker for tItrATing hIgh flOw Nasal Cannula Therapy |
NOT_YET_RECRUITING | |
| NCT07484802 |
Vela Generation II: Usability and Performance of a Non-Invasive Ventilation Mask. |
NOT_YET_RECRUITING | NA |
| NCT07437846 |
Impact of PEEP on Respiratory Effort During Assisted Ventilation |
RECRUITING | NA |
| NCT07419438 |
Supraglottic Airway for Resuscitation in Preemies |
RECRUITING | NA |
| NCT07411976 |
Critical Care Admission Following Emergency Department's Resuscitation Room Care |
NOT_YET_RECRUITING | |
| NCT07380607 |
Double Triggering Asynchrony in Mechanically Ventilated Patients. |
COMPLETED |
