Respiratory failure is a serious condition in which the body cannot adequately oxygenate blood and/or remove carbon dioxide. It can present as hypoxemic or hypercapnic respiratory failure and may be fatal without prompt treatment.
England will screen all newborns for SMA after Jesy Nelson's campaign. A real-world study found Zolgensma helped children with SMA achieve motor milestones, with newborn screening leading to earlier gains.
Researchers at MD Anderson developed an extracellular vesicle-based platform that delivers full-length DMD mRNA, restoring dystrophin production and improving muscle function in preclinical Duchenne muscular dystrophy models. The study, published in Nature Biomedical Engineering, showed reduced side effects compared with viral gene therapies.
Recent studies reveal AI chatbots face significant challenges in medical applications, with one study showing ChatGPT Health under-triaged 51.6% of emergency cases. Cancer patients using an AI chatbot experienced 22% withdrawal rates due to usability issues, while medical researchers show cautious adoption with 40.3% reporting AI use in research.
The FDA has placed a partial hold on U.S. enrollment in a Phase 2 trial of del-desiran for myotonic dystrophy type 1, citing preclinical mouse data showing blood pressure drops not seen in humans, following a serious adverse event in earlier testing.
The FDA approved Zycubo (copper histidinate) on January 13, 2026, as the first treatment for Menkes disease in pediatric patients, following resolution of manufacturing compliance concerns that led to an initial rejection in September 2025.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07766681 |
Epidural Spinal Cord Stimulation for Respiratory Recovery in Brain Injury |
NOT_YET_RECRUITING | NA |
| NCT07722130 |
Epidural Spinal Cord Stimulation for Respiratory Recovery in Cervical SCI |
RECRUITING | NA |
| NCT07701850 |
Mechanical Ventilator Adjustments and Patient Dyspnea |
NOT_YET_RECRUITING | NA |
| NCT07658131 |
External Validation of AI-Aided Weaning Software Using Multicenter Retrospective Data |
COMPLETED | |
| NCT07620912 |
Sedation vs No Sedation in Mechanically Ventilated COPD Patients |
COMPLETED | PHASE2 |
| NCT07613918 |
Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children |
NOT_YET_RECRUITING | |
| NCT07542093 |
Bedside Lung Ultrasound to Monitor Lung Recruitment in Obese Patients |
NOT_YET_RECRUITING | |
| NCT07536750 |
Comparison of the Efficacy and Safety of Ciprofol Versus Propofol for Sedation in ICU Patients Undergoing Non-Invasive Ventilation |
RECRUITING | |
| NCT07522450 |
Benefit of Sleep Quality Monitoring by EEG in ICU |
RECRUITING | |
| NCT07521254 |
Noninvasive Technique and High Flow Nasal Oxygen in Respiratory Failure |
RECRUITING | NA |
