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Effect of Nava on Weaning Outcome in Patients With Mechanical Ventilation

NCT05219643 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 130

Last updated 2026-04-29

No results posted yet for this study

Summary

This study intends to compare the effects of NAVA and PSV on weaning success rate and mechanical ventilation time in patients with tracheotomy patients through a randomized controlled study.

Conditions

  • ARDS

Interventions

DEVICE

NAVA

Nava level is set to maintain the target tidal volume: 6-10ml / kg (pbw). The trigger sensitivity is 0.5uv. The expiratory trigger sensitivity: the built-in software of the ventilator is set to 70% of the peak value of diaphragm electrical activity.

DEVICE

PSV

According to the doctor's experience, maintain the target tidal volume: 6-10ml / kg (pbw); trigger sensitivity: 1.5-2l/min, expiratory trigger sensitivity: 30% inspiratory peak flow rate.

Sponsors & Collaborators

  • First Affiliated Hospital of Wannan Medical College

    collaborator OTHER

  • Southeast University, China

    lead OTHER

Principal Investigators

  • Liu Ling, MD · Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-26
Primary Completion
2025-02-27
Completion
2025-02-27

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05219643 on ClinicalTrials.gov