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Comparison of Breathing Pattern During Neurally Adjusted Ventilatory Assist Ventilation and Pressure Support Ventilation

NCT01614873 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2013-04-12

No results posted yet for this study

Summary

Comparison of Breathing pattern during mechanical ventilation. Two modes of mechanical ventilation are compared (Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist)

Conditions

  • Respiratory System Abnormalities

Interventions

DEVICE

Servo-i® ventilator, MAQUET,Critical Care, Sweden

Electrical activity of the diaphragm will be obtained through a naso-gastric tube with multiple array of electrodes placed at its distal end (Eadi catheter® , Maquet Critical Care, Sweden). Subject will be ventilated with a mouthpiece interface. NAVA will be compared to Pressure Support using the same ventilator. Once the pattern of breathing will be stabilized (10 minutes) in each condition (see arm) the following parameters will be recorded during 5 minutes and compared : tidal volume, inspiratory time, expiratory time, transcutaneous CO2 pressure, diaphragmatic Emg activity, delay between the inspiratory activity initiation and positive pressure initiation, delay between the end of the inspiratory effort and the end of pressurisation.

Sponsors & Collaborators

  • Adep Assistance

    collaborator OTHER

  • Centre d'Investigation Clinique et Technologique 805

    lead OTHER

Principal Investigators

  • Frédéric Lofaso, MD-PhD · Hopital Raymond Poincare - Garches - France

  • Nicolas Terzi, MD-PhD · CHU de Caen - INSERM U1075 - France

  • Pascale Calabrese, PhD · Laboratoire TIMC-IMAG - La Tronche - France

  • Henri Meric · EA 4497 - Hopital Raymond Poincare - Garches -France

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-05-31
Primary Completion
2012-05-31
Completion
2012-08-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01614873 on ClinicalTrials.gov