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How Does Dietary Carbohydrate Influence the Formation of an Atherogenic Lipoprotein Phenotype (ALP)?

NCT01790984 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 27

Last updated 2021-05-27

Study results available
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Summary

The hypothesis of this study is that a diet high in sugars will increase abnormalities in blood lipids which are associated with increased cardiovascular disease risk, relative to a diet which is low in sugar. We predict that this potentially adverse effect of dietary sugars on blood lipids will be more pronounced in people with a raised level of stored fat inside their liver, as compared to people with a low level of stored fat.

Conditions

  • Non-alcoholic Fatty Liver Disease (NAFLD)

Interventions

OTHER

High sugar low starch diet

OTHER

Low sugar high starch diet

Sponsors & Collaborators

  • Imperial College London

    collaborator OTHER

  • University of Cambridge

    collaborator OTHER

  • Bruce A. Griffin

    lead OTHER

Principal Investigators

  • Bruce A Griffin, PhD · University of Surrey

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-04-30
Primary Completion
2011-08-31
Completion
2012-09-30

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01790984 on ClinicalTrials.gov