Role of Milk Fat Globule Membranes in Dairy Foods: Health Effects in Humans

Summary

Investigate the effects of milk fat with or without milk fat globule membranes (MFGM) on blood lipid profile, vascular function, insulin sensitivity, inflammation and gene expression. Overweight subjects will be randomized to one of 2 groups with different types of dairy products: 1)butter oil; 2) cream (milk fat with MFGM).

Conditions

• Hypercholesterolemia

Interventions

DIETARY_SUPPLEMENT

Butter oil

Daily intake of 40 g butter oil

DIETARY_SUPPLEMENT

Cream

Daily intake of 100 g cream (40%)

Sponsors & Collaborators

• Lund University

  collaborator OTHER

• LRF Mjölk, Sweden

  collaborator UNKNOWN

• Arla Foods

  collaborator INDUSTRY

• Skånemejerier, Sweden

  collaborator UNKNOWN

• Semper AB, Sweden

  collaborator UNKNOWN

• The Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS)

  collaborator OTHER_GOV

• Swedish Nutrition Foundation SNF

  collaborator UNKNOWN

• Vinnova

  collaborator OTHER_GOV

• The Swedish Farmers' Foundation for Agricultural Research

  collaborator UNKNOWN

• Livsmedelsföretagen, Sweden

  collaborator UNKNOWN

• Svensk Dagligvaruhandel, Sweden

  collaborator UNKNOWN

• Uppsala University

  lead OTHER

Principal Investigators

• Ulf Risérus, Assoc prof · Uppsala University

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

20 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2013-02-28

Primary Completion

2013-06-30

Completion

2013-06-30

Countries

• Sweden

Study Locations