Strategies for Personalised Nutrition

Summary

The concept of personalised nutrition emerged following the sequencing of the human genome in 2000. It was hoped that with the identification of gene nutrient interactions, an individual's response and susceptibility to particular diets would be better understood and therefore appropriate dietary modifications could be made to optimise health and lower disease risk. Then Food4Me aims to study the development of personalized nutrition at three levels and determine whether providing more personalised dietary advice leads to better compliance and health outcomes compared to standard population advice.

The hypotheses to be tested in the Food4Me study are as follows:

* Personalisation of dietary advice assists and/or motivates consumers to eat a healthier diet and follow a healthier lifestyle (in comparison with "impersonal" \[conventional\] dietary advice).
* Personalisation based on individualised biochemical (phenotypic) and/or genetic information is more effective in assisting and/or motivating study participants to make, and to sustain, appropriate healthy changes to their usual (habitual) diet and lifestyle.

Conditions

• Dietary Modification

Interventions

BEHAVIORAL

Level 1

Level 1 - Participants will receive personalised dietary advice based on their dietary intake data alone.

BEHAVIORAL

Level 2

Level or Group 2: Participants will receive personalised dietary advice taking dietary intake and phenotypic data into account.

BEHAVIORAL

Level 3

Level or group 3: Participants will receive personalised dietary advice taking dietary intake, phenotypic and genotypic data into account.

BEHAVIORAL

Level 0

Level 0 - Control group - Investigators will provide non-personalized dietary advice for improved food choice based on standard population healthy eating guidelines.

Sponsors & Collaborators

• University College Dublin

  collaborator OTHER

• Maastricht University

  collaborator OTHER

• University of Oslo

  collaborator OTHER

• University of Navarra

  collaborator OTHER

• Harokopio University

  collaborator OTHER

• University of Reading

  collaborator OTHER

• National Food and Nutrition InstitutE

  collaborator UNKNOWN

• Technical University of Munich

  collaborator OTHER

• University of Newcastle Upon-Tyne

  collaborator OTHER

• Newcastle University

  lead OTHER

Principal Investigators

• John Mathers, Professor · Newcastle University, United Kingdom

• Mike Gibney, Professor · University College Dublin, Ireland

• Wim Saris, Professor · •Universiteit Maastricht, Netehrlands

• Alfredo Martinez, Professor · University of Navarra, Spain

• Julie Lovegrove, Professor · University of Reading, United Kingdom

• Yannis Manios, Professor · Harokopio University, Athens, Greece

• Iwona Traczyk, Professor · National Food and Nutrition Institute, Warsaw, Poland

• Hannelore Daniel, Professor · Technische Universitaet Muenchen, Germany

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2012-08-31

Primary Completion

2014-08-31

Completion

2014-12-31

Countries

• Germany
• Greece
• Ireland
• Netherlands
• Poland
• Spain
• United Kingdom

Study Locations