Hyperlipidemia is a disorder of elevated lipids in the blood, including cholesterol and/or triglycerides, and is a major modifiable risk factor for atherosclerotic cardiovascular disease. It may be primary (genetic) or secondary to diet, obesity, diabetes, hypothyroidism, and medications. Management includes lifestyle interventions and lipid-lowering drugs.
New research: any cardiometabolic risk factor justifies MASLD screening in overweight adults, and MASLD independently worsens sepsis, bleeding, and other outcomes in hospitalized Crohn's disease patients.
A botanical moisturizer with oat and aloe outperformed metronidazole for rosacea erythema and lesions over 12 weeks. A separate study found nine risk factors for rosacea severity, including female sex, family history, and skin care habits.
Researchers have discovered that vitamin B3 (niacin) can effectively target microRNA-93, a key genetic driver of fatty liver disease. The study shows niacin reduces miR-93 levels and increases SIRT1 activity, restoring normal fat-processing pathways in the liver. This finding suggests a widely available vitamin could become a new treatment for metabolic-associated fatty liver disease affecting 30% of people globally.
New research demonstrates blood-based biomarkers can predict testicular cancer recurrence and treatment outcomes, while separate study reveals long-term health risks vary by chemotherapy regimen in survivors.
Study of 3600 older adults with type 1 diabetes across US and European registries reveals significant gaps in guideline-recommended cardiovascular therapies and diabetes technology use despite high disease burden.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07730567 |
A Study to Evaluate the Pharmacokinetic Interaction and the Safety of AD-236A and AD-236B |
NOT_YET_RECRUITING | PHASE1 |
| NCT07722299 |
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAL0167 in Healthy Participants |
NOT_YET_RECRUITING | PHASE1 |
| NCT07720232 |
Bacillus Subtilis and Enterococcus Faecium Probiotic Plus Lipid-Lowering Therapy for Hypertriglyceridemic Acute Pancreatitis: A Prospective RCT |
RECRUITING | PHASE4 |
| NCT07712042 |
Tafolecimab in Hyperlipidemia: A Study of Different Dosing Intervals |
NOT_YET_RECRUITING | |
| NCT07710898 |
Amelioration of Lipid Profile Through Date Cider-vinegar Along With 5:2 Intermittent Fasting |
COMPLETED | NA |
| NCT07696559 |
Effect of the β-sitosterol-enriched Dietary Plan on Lipid Levels. |
COMPLETED | NA |
| NCT07685639 |
Electronic Health Record Augmented LDL-Cholesterol Optimization and Control Via Active Lipid Engagement (EHR-LOCALE): A Quality Improvement Implementation Study |
NOT_YET_RECRUITING | NA |
| NCT07674524 |
Management Strategy of 1L Lorlatinib With Hyperlipidemia in Stage IIIB-IV ALK Positive NSCLC |
NOT_YET_RECRUITING | |
| NCT07662330 |
Assessment of the Effects and Safety of Spermidine Supplementation on Blood Lipids and Body Weight in Overweight or Obese Individuals With Hyperlipidemia |
RECRUITING | NA |
| NCT07588256 |
New Taipei City 888 Digital Medical AI Platform for Prevention and Care of the Three Highs and Cardio-Renal-Vascular Diseases |
RECRUITING | NA |
