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Dose-dependent Effects of Blueberry Polyphenols on Endothelial Function in Healthy Individuals

NCT01829542 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 11

Last updated 2013-04-11

No results posted yet for this study

Summary

The purpose of this study is to assess the impact of acute blueberry polyphenol intake on endothelial function of healthy volunteers. Specifically, the investigators plan to perform a randomised, double blind, cross-over human intervention trial using a blueberry drink to investigate the dose-dependent effects of blueberry polyphenols on blood vessel function using Flow mediated dilation (FMD) to measure endothelial function. The study will not only measure the acute effects of flavonoid ingestion on vascular reactivity but will also assess plasma polyphenol metabolite levels.

Conditions

  • Endothelial Function

Interventions

DIETARY_SUPPLEMENT

Freeze-dried blueberry powder dissolved in water

Wild blueberry freeze-dried powder dissolved in water

DIETARY_SUPPLEMENT

Control

Macro- and micro-nutrient matched control in water

Sponsors & Collaborators

  • Alpro Foundation

    collaborator OTHER

  • University of Reading

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-05-31
Primary Completion
2012-08-31
Completion
2012-10-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01829542 on ClinicalTrials.gov