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Effects of Antioxidants on Cardiovascular Risk Measures (Spice Study)

NCT00954902 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2018-01-25

No results posted yet for this study

Summary

The purpose of this study is to assess whether feeding highly antioxidant spices of providing these same antioxidants as capsules is able to affect cardiovascular risk measures. Because this is a new area of research, the investigators will use many measures to assess this question including blood markers, tests of blood vessel health, measures of blood pressure responses, measures of clotting activity, and other inflammation measures.

Conditions

Interventions

DIETARY_SUPPLEMENT

High Antioxidant Spice Blend

14.5 g spice blend incorporated into a delivery meal including: cloves, cinnamon, oregano, rosemary, ginger, black pepper, paprika, garlic powder, and turmeric.

BEHAVIORAL

Trier Psychological Stressor

This is a psychological stressor that is used to invoked stress responses in human subjects. Subjects are told they are taped and evaluated and deliver the speech in front of a trained panel of judges.

OTHER

Placebo antioxidant concentrate

Placebo capsules

Sponsors & Collaborators

  • McCormick Science Institute

    collaborator INDUSTRY

  • Penn State University

    lead OTHER

Principal Investigators

  • Sheila G. West, PhD · Penn State

  • Ann C. Skulas-Ray, B.S. · Penn State

  • Penny M. Kris-Etherton, PhD, RD · Penn State

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
30 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-08-31
Primary Completion
2010-09-30
Completion
2010-09-30

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00954902 on ClinicalTrials.gov