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Dietary Sodium, Oxidative Stress, and Pulsatile Hemodynamics

NCT04233957 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2023-11-29

No results posted yet for this study

Summary

High sodium diets impair vascular function, which may influence the work of the heart. This investigation is designed to determine if this change in vascular function results in a greater workload in the heart and if people who regularly exercise are protected from these effects.

Conditions

  • Sodium Excess

Interventions

DIETARY_SUPPLEMENT

High Sodium

10 days of 3900 mg of sodium/day in excess of normal dietary intake delivered via enteric capsules filled with table salt.

OTHER

Placebo

10 days of enteric capsules filled with dextrose.

Sponsors & Collaborators

  • University of Delaware

    lead OTHER

Principal Investigators

  • David G Edwards, PhD · University of Delaware

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-01-01
Primary Completion
2024-06-30
Completion
2024-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04233957 on ClinicalTrials.gov