Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation
NCT00457847 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1150
Last updated 2025-07-16
Summary
Primary graft dysfunction (PGD) is a severe lung injury that can occur in the days following lung transplant surgery. The purpose of this study is to identify genetic factors that may put someone at risk for developing PGD.
Conditions
- Primary Graft Dysfunction
- Lung Transplantation
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH - collaborator OTHER
-
Vanderbilt University
collaborator OTHER - collaborator OTHER
-
University of Alabama at Birmingham
collaborator OTHER - collaborator OTHER
- collaborator OTHER
- collaborator OTHER
-
University of Pittsburgh
collaborator OTHER -
University of Chicago
collaborator OTHER - lead OTHER
Principal Investigators
-
Jason D. Christie, MD · University of Pennsylvania
Eligibility
- Min Age
- 15 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-02-28
- Primary Completion
- 2026-06-30
- Completion
- 2026-06-30
Countries
- United States
Study Locations
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