Three FcRn inhibitors are approved for generalized myasthenia gravis, with a head-to-head trial of efgartigimod and nipocalimab underway. Emerging therapies including telitacicept, gefurulimab, and CAR-T cell therapy (KYV-101) show promise, while Immunovant's batoclimab failed TED trials.
Researchers at McMaster University said their SyntheMol-RL AI model designed a new antibiotic candidate called synthecin. In mouse wound infection models, the topical compound was highly effective against drug-resistant Staphylococcus aureus.
The FDA approved Bracco's Vueway for neonates and infants at half the standard gadolinium dose, accepted Bayer's gadoquatrane application for a 60% dose reduction, and granted Breakthrough Device designation to Radiology Partners' AI chest X-ray tool.
Researchers at Stanford and Harvard are developing nasal spray vaccines offering broad protection against respiratory infections, with early animal and phase 1 human trials showing safety and potential efficacy.
National Institutes of Health Director Jay Bhattacharya will serve as acting director of the Centers for Disease Control and Prevention following Jim O'Neill's departure. Bhattacharya will oversee both agencies simultaneously as the CDC faces significant instability.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07616908 |
Effect of Miralax NPO Time on Residual Gastric Volumes and Bowel Preparation |
NOT_YET_RECRUITING | NA |
| NCT07615270 |
A Pilot Study of Anselamimab in Patients With AL Amyloidoma and Measurable Tissue Involvement |
NOT_YET_RECRUITING | EARLY_PHASE1 |
| NCT07610785 |
Standardized Adaptive Music Medicine for Suicidality |
NOT_YET_RECRUITING | NA |
| NCT07609303 |
Pediatric Solid Organ Transplant Patient Engagement Using an Educational Tablet-Based Game(Mystic Wizard) |
NOT_YET_RECRUITING | NA |
| NCT07606846 |
Exteriorization Versus In Situ Hysterotomy Repair During Cesarean: Effects on Uterine Tone |
NOT_YET_RECRUITING | NA |
| NCT07606443 |
COMUNICAR: Community-Led Family-Centered Communication for Cancer Survivorship Care |
NOT_YET_RECRUITING | NA |
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Feasibility Study of a Remote Behavioral Dietary Intervention in Patients With Early to Intermediate AMD: Glucose Lowering for Vision Extension |
NOT_YET_RECRUITING | NA |
| NCT07601295 |
Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH) |
NOT_YET_RECRUITING | PHASE2 |
| NCT07601061 |
Simplifying Diet Tracking in a Digital Weight Loss Intervention |
NOT_YET_RECRUITING | NA |
| NCT07600658 |
A Phase I/II, First-In-Human Trial to Evaluate the Safety, Tolerability, and Pharmacokinetic Activity to Prevent or Treat Neuropsychiatric Symptoms in Pediatric Subjects With Timothy Syndrome |
NOT_YET_RECRUITING | PHASE1/PHASE2 |
