MedTrace Logo

Incidence, Risk Factors and Outcomes of Diaphragm Dysfunction After Lung Transplantation

NCT04103996 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2024-12-11

No results posted yet for this study

Summary

The study is designed to characterize the changes in diaphragm function after lung transplantation.

Conditions

  • Diaphragm Injury
  • Lung Transplant; Complications, Mechanical
  • Respiratory Failure
  • Mechanical Ventilation Complication

Interventions

DIAGNOSTIC_TEST

Ultrasound

Sonographic measurements (diaphragm, abdominal muscle, and quadriceps thickness) will be acquired when listed for lung transplantation. Sonographic measurements will be recorded on a daily basis for up to 1 week after transplantation (while the patient remains intubated).

DIAGNOSTIC_TEST

Respiratory function measurements

Maximal expiratory pressure (MEP) and maximal inspiratory pressure (MIP) will be acquired after listing for lung transplantation. After transplant, MIP will be recorded once patients are eligible for a trial of spontaneous breathing and weekly thereafter. MEP will also be recorded at ICU discharge.

Sponsors & Collaborators

  • University Health Network, Toronto

    lead OTHER

Principal Investigators

  • Ewan Goligher, MD, PhD · UHN Toronto

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-02-10
Primary Completion
2021-12-31
Completion
2021-12-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04103996 on ClinicalTrials.gov